Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function

Diabetes mellitus is a growing health care problem, resulting in significant cardiovascular morbidity and mortality. Diabetes also increases the risk for heart failure (HF) and decreased cardiac myocyte function, which are linked to changes in cardiac mitochondrial energy metabolism. The free mitoch...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Suarez, Jorge, Cividini, Federico, Scott, Brian T., Lehmann, Kim, Diaz-Juarez, Julieta, Diemer, Tanja, Dai, Anzhi, Suarez, Jorge A., Jain, Mohit, Dillmann, Wolfgang H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971443/
https://ncbi.nlm.nih.gov/pubmed/29626093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002066
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