Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function

Diabetes mellitus is a growing health care problem, resulting in significant cardiovascular morbidity and mortality. Diabetes also increases the risk for heart failure (HF) and decreased cardiac myocyte function, which are linked to changes in cardiac mitochondrial energy metabolism. The free mitoch...

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Foilsithe in:J Biol Chem
Main Authors: Suarez, Jorge, Cividini, Federico, Scott, Brian T., Lehmann, Kim, Diaz-Juarez, Julieta, Diemer, Tanja, Dai, Anzhi, Suarez, Jorge A., Jain, Mohit, Dillmann, Wolfgang H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Molecular Bases of Disease
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971443/
https://ncbi.nlm.nih.gov/pubmed/29626093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002066
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