Comparison of Sequencing Platforms for Single Nucleotide Variant Calls in a Human Sample

Next-generation sequencings platforms coupled with advanced bioinformatic tools enable re-sequencing of the human genome at high-speed and large cost savings. We compare sequencing platforms from Roche/454(GS FLX), Illumina/HiSeq (HiSeq 2000), and Life Technologies/SOLiD (SOLiD 3 ECC) for their abil...

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Detalhes bibliográficos
Main Authors: Ratan, Aakrosh, Miller, Webb, Guillory, Joseph, Stinson, Jeremy, Seshagiri, Somasekar, Schuster, Stephan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566181/
https://ncbi.nlm.nih.gov/pubmed/23405114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055089
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