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Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance
Morphine and related µ-opioid receptor (MOR) agonists remain among the most effective drugs known for acute relief of severe pain. A major problem in treating painful conditions is that tolerance limits the long-term utility of opioid agonists. Considerable effort has been expended on developing an...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565916/ https://ncbi.nlm.nih.gov/pubmed/23321159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.112.005942 |
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