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In situ protein expression of RRM1, ERCC1 and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy

Ribonucleotide reductase 1 (RRM1) is a determinant of gemcitabine efficacy in non-small cell lung cancer and pancreatic cancer. We investigated the protein levels of RRM1 and two other DNA repair enzymes, ERCC1 and BRCA1, in 55 metastatic breast cancer (MBC) patients undergoing gemcitabine-based che...

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Bibliografische gegevens
Hoofdauteurs: Metro, G., Zheng, Z., Fabi, A., Schell, M., Antoniani, B., Mottolese, M., Monteiro, A.N., Vici, P., Rivera, S. Lara, Boulware, D., Cognetti, F., Bepler, G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565222/
https://ncbi.nlm.nih.gov/pubmed/19968494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357900903095722
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