In situ protein expression of RRM1, ERCC1 and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy

Ribonucleotide reductase 1 (RRM1) is a determinant of gemcitabine efficacy in non-small cell lung cancer and pancreatic cancer. We investigated the protein levels of RRM1 and two other DNA repair enzymes, ERCC1 and BRCA1, in 55 metastatic breast cancer (MBC) patients undergoing gemcitabine-based che...

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Detalhes bibliográficos
Main Authors: Metro, G., Zheng, Z., Fabi, A., Schell, M., Antoniani, B., Mottolese, M., Monteiro, A.N., Vici, P., Rivera, S. Lara, Boulware, D., Cognetti, F., Bepler, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565222/
https://ncbi.nlm.nih.gov/pubmed/19968494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357900903095722
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