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In situ protein expression of RRM1, ERCC1 and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy

Ribonucleotide reductase 1 (RRM1) is a determinant of gemcitabine efficacy in non-small cell lung cancer and pancreatic cancer. We investigated the protein levels of RRM1 and two other DNA repair enzymes, ERCC1 and BRCA1, in 55 metastatic breast cancer (MBC) patients undergoing gemcitabine-based che...

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Библиографические подробности
Главные авторы: Metro, G., Zheng, Z., Fabi, A., Schell, M., Antoniani, B., Mottolese, M., Monteiro, A.N., Vici, P., Rivera, S. Lara, Boulware, D., Cognetti, F., Bepler, G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565222/
https://ncbi.nlm.nih.gov/pubmed/19968494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357900903095722
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