Randomized Phase III Trial of Gemcitabine-Based Chemotherapy With In Situ RRM1 and ERCC1 Protein Levels for Response Prediction in Non–Small-Cell Lung Cancer

PURPOSE: We evaluated the efficacy of gemcitabine versus gemcitabine and carboplatin in patients with advanced non–small-cell lung cancer (NSCLC) and a performance status (PS) of 2 and assessed if tumoral RRM1 and ERCC1 protein levels are predictive of response to therapy. PATIENTS AND METHODS: A ra...

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Detalhes bibliográficos
Main Authors: Reynolds, Craig, Obasaju, Coleman, Schell, Michael J., Li, Xueli, Zheng, Zhong, Boulware, David, Caton, John R., DeMarco, Linda C., O'Rourke, Mark A., Shaw Wright, Gail, Boehm, Kristi A., Asmar, Lina, Bromund, Jane, Peng, Guangbin, Monberg, Matthew J., Bepler, Gerold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793001/
https://ncbi.nlm.nih.gov/pubmed/19884554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.21.9766
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