Exomic Sequencing of Medullary Thyroid Cancer Reveals Dominant and Mutually Exclusive Oncogenic Mutations in RET and RAS

CONTEXT: Medullary thyroid cancer (MTC) is a rare thyroid cancer that can occur sporadically or as part of a hereditary syndrome. OBJECTIVE: To explore the genetic origin of MTC, we sequenced the protein coding exons of approximately 21,000 genes in 17 sporadic MTCs. PATIENTS AND DESIGN: We sequence...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Agrawal, Nishant, Jiao, Yuchen, Sausen, Mark, Leary, Rebecca, Bettegowda, Chetan, Roberts, Nicholas J., Bhan, Sheetal, Ho, Allen S., Khan, Zubair, Bishop, Justin, Westra, William H., Wood, Laura D., Hruban, Ralph H., Tufano, Ralph P., Robinson, Bruce, Dralle, Henning, Toledo, Sergio P. A., Toledo, Rodrigo A., Morris, Luc G. T., Ghossein, Ronald A., Fagin, James A., Chan, Timothy A., Velculescu, Victor E., Vogelstein, Bert, Kinzler, Kenneth W., Papadopoulos, Nickolas, Nelkin, Barry D., Ball, Douglas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565108/
https://ncbi.nlm.nih.gov/pubmed/23264394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-2703
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados