Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells

Here we develop nanoparticles composed of lipid-like materials (lipidoids) to facilitate non-viral delivery of small interfering RNA (siRNA) to endothelial cells (ECs). Nanoparticles composed of siRNA and lipidoids with small size (~200 nm) and positive charge (~34 mV) were formed by self assembly o...

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Detalhes bibliográficos
Main Authors: Cho, Seung-Woo, Goldberg, Michael, Son, Sun Mi, Xu, Qiaobing, Yang, Fan, Mei, Ying, Bogatyrev, Said, Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564673/
https://ncbi.nlm.nih.gov/pubmed/23393492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.200900519
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