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Delivery of Small Interfering RNA for Inhibition of Endothelial Cell Apoptosis by Hypoxia and Serum Deprivation

RNA interference (RNAi) for anti-angiogenic or pro-apoptotic factors in endothelial cells (ECs) has great potential for the treatment of ischemic diseases by promoting angiogenesis or inhibiting apoptosis. Here, we report the utility of small interfering RNA (siRNA) in inhibiting EC apoptosis induce...

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Détails bibliographiques
Auteurs principaux: Cho, Seung-Woo, Hartle, Lauren, Son, Sun Mi, Yang, Fan, Goldberg, Michael, Xu, Qiaobing, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957099/
https://ncbi.nlm.nih.gov/pubmed/18765230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.123
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