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Polyamine analogues targeting epigenetic gene regulation
Over the past three decades the metabolism and functions of the polyamines have been actively pursued as targets for antineoplastic therapy. Interactions between cationic polyamines and negatively charged nucleic acids play a pivotal role in DNA stabilization and RNA processing that may affect gene...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564236/ https://ncbi.nlm.nih.gov/pubmed/20095972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/bse0460007 |
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