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The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines

Aberrant epigenetic silencing of tumor suppressor genes is a common feature observed during the transformation process of many cancers, including those of hematologic origin. Histone modifications, including acetylation, phosphorylation, and methylation, collaborate with DNA CpG island methylation t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Murray-Stewart, Tracy, Woster, Patrick M., Casero, Robert A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692581/
https://ncbi.nlm.nih.gov/pubmed/23508577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-013-1485-1
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