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Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease

Mitochondrial dysfunction caused by protein aggregation has been shown to have an important role in neurological diseases, such as Parkinson's disease (PD). Mitochondria have evolved at least two levels of defence mechanisms that ensure their integrity and the viability of their host cell. Firs...

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書目詳細資料
Main Authors: Costa, A C, Loh, S H Y, Martins, L Miguel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563993/
https://ncbi.nlm.nih.gov/pubmed/23328674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.205
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