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δ-opioid receptor activation protects against Parkinson’s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy
Our previous studies have shown that the δ-opioid receptor (DOR) is an important neuroprotector via the regulation of PTEN-induced kinase 1 (PINK1), a mitochondria-related molecule, under hypoxic and MPP(+) insults. Since mitochondrial dysfunctions are observed in both hypoxia and MPP(+) insults, th...
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| Vydáno v: | Aging (Albany NY) |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7803568/ https://ncbi.nlm.nih.gov/pubmed/33197884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103970 |
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