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Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease

Mitochondrial dysfunction caused by protein aggregation has been shown to have an important role in neurological diseases, such as Parkinson's disease (PD). Mitochondria have evolved at least two levels of defence mechanisms that ensure their integrity and the viability of their host cell. Firs...

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Detalhes bibliográficos
Main Authors: Costa, A C, Loh, S H Y, Martins, L Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563993/
https://ncbi.nlm.nih.gov/pubmed/23328674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.205
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