Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression and improves chemotherapeutic responses

Tumor-infiltrating immune cells can promote chemoresistance and metastatic spread in aggressive tumors. Consequently, the type and quality of immune responses present in the neoplastic stroma are highly predictive of patient outcome in several cancer types. In addition to host immune responses, intr...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Mitchem, Jonathan B., Brennan, Donal J., Knolhoff, Brett L., Belt, Brian A., Zhu, Yu, Sanford, Dominic E., Belaygorod, Larisa, Carpenter, Danielle, Collins, Lynne, Piwnica-Worms, David, Hewitt, Stephen, Udupi, Girish Mallya, Gallagher, William M., Wegner, Craig, West, Brian L., Wang-Gillam, Andrea, Goedegebuure, S Peter, Linehan, David C., DeNardo, David G.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2012
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563931/
https://ncbi.nlm.nih.gov/pubmed/23221383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2731
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