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IL-2R signaling is essential for functional maturation of T regulatory cells during thymic development()

CD4(+) Foxp3(+) Tregs are an independent cell lineage and their developmental progression during thymic development depends on IL-2R signaling. However, the role of IL-2R signaling during thymic Treg development remains only partially understood. The current study assessed the contribution of IL-2 i...

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Autori principali: Cheng, Guoyan, Yu, Aixin, Dee, Michael J., Malek, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563871/
https://ncbi.nlm.nih.gov/pubmed/23315074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201218
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