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MERTK Interactions with SH2-Domain Proteins in the Retinal Pigment Epithelium

The receptor tyrosine kinase MERTK plays an essential role in the phagocytic uptake of shed photoreceptor membranes by the retinal pigment epithelium (RPE). A fundamental aspect of signal transduction by receptor tyrosine kinases involves autophosphorylation of tyrosine residues that recruit Src-hom...

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Autori principali: Shelby, Shameka J., Colwill, Karen, Dhe-Paganon, Sirano, Pawson, Tony, Thompson, Debra A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563642/
https://ncbi.nlm.nih.gov/pubmed/23390493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053964
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