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Mertk Deficiency Alters Expression of microRNAs in the Retinal Pigment Epithelium Cells

Phagocytic clearance of the spent photoreceptor outer segments (OS) by RPE cells is regulated by circadian rhythm cycle and is essential for photoreceptor integrity and function. Mertk regulates RPE phagocytosis and a deficiency in Mertk causes photoreceptor degeneration and visual loss. This study...

詳細記述

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書誌詳細
出版年:Metab Brain Dis
主要な著者: Tang, Yong, Lu, Qingjun, Wei, Yunrong, Han, Lixia, Ji, Rui, Li, Qiutang, Lu, Qingxian
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492868/
https://ncbi.nlm.nih.gov/pubmed/25604732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-015-9653-5
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