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Mertk Deficiency Alters Expression of microRNAs in the Retinal Pigment Epithelium Cells
Phagocytic clearance of the spent photoreceptor outer segments (OS) by RPE cells is regulated by circadian rhythm cycle and is essential for photoreceptor integrity and function. Mertk regulates RPE phagocytosis and a deficiency in Mertk causes photoreceptor degeneration and visual loss. This study...
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| 出版年: | Metab Brain Dis |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492868/ https://ncbi.nlm.nih.gov/pubmed/25604732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-015-9653-5 |
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