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Microphthalmia-associated Transcription Factor (MITF) Promotes Differentiation of Human Retinal Pigment Epithelium (RPE) by Regulating microRNAs-204/211 Expression

The retinal pigment epithelium (RPE) plays a fundamental role in maintaining visual function and dedifferentiation of RPE contributes to the pathophysiology of several ocular diseases. To identify microRNAs (miRNAs) that may be involved in RPE differentiation, we compared the miRNA expression profil...

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Detalhes bibliográficos
Main Authors: Adijanto, Jeffrey, Castorino, John J., Wang, Zi-Xuan, Maminishkis, Arvydas, Grunwald, Gerald B., Philp, Nancy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370234/
https://ncbi.nlm.nih.gov/pubmed/22523078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.354761
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