Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae

BACKGROUND: Acetoin is an important bio-based platform chemical. However, it is usually existed as a minor byproduct of 2,3-butanediol fermentation in bacteria. RESULTS: The present study reports introducing an exogenous NAD(+) regeneration sysytem into a 2,3-butanediol producing strain Klebsiella p...

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Bibliographic Details
Main Authors: Ji, Xiao-Jun, Xia, Zhi-Fang, Fu, Ning-Hua, Nie, Zhi-Kui, Shen, Meng-Qiu, Tian, Qian-Qian, Huang, He
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563507/
https://ncbi.nlm.nih.gov/pubmed/23351660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-6834-6-7
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