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Redistribution of Carbon Flux toward 2,3-Butanediol Production in Klebsiella pneumoniae by Metabolic Engineering

Klebsiella pneumoniae KCTC2242 has high potential in the production of a high-value chemical, 2,3-butanediol (2,3-BDO). However, accumulation of metabolites such as lactate during cell growth prevent large-scale production of 2,3-BDO. Consequently, we engineered K. pneumoniae to redistribute its car...

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Detalhes bibliográficos
Main Authors: Kim, Borim, Lee, Soojin, Jeong, Daun, Yang, Jeongmo, Oh, Min-Kyu, Lee, Jinwon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203659/
https://ncbi.nlm.nih.gov/pubmed/25329548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105322
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