Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions

BACKGROUND: Cancer, much like most human disease, is routinely studied by utilizing model organisms. Of these model organisms, mice are often dominant. However, our assumptions of functional equivalence fail to consider the opportunity for divergence conferred by ~180 Million Years (MY) of independe...

Full description

Saved in:
Bibliographic Details
Main Authors: Morgan, Claire C, Shakya, Kabita, Webb, Andrew, Walsh, Thomas A, Lynch, Mark, Loscher, Christine E, Ruskin, Heather J, O’Connell, Mary J
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563467/
https://ncbi.nlm.nih.gov/pubmed/22788692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-114
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items