Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response

BACKGROUND: Clostridium difficile is a nosocomial pathogen prevalent in hospitals worldwide and increasingly common in the community. Sequence differences have been shown to be present in the Surface Layer Proteins (SLPs) from different C. difficile ribotypes (RT) however whether these differences i...

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Detalhes bibliográficos
Publicado no:BMC Evol Biol
Main Authors: Lynch, Mark, Walsh, Thomas A., Marszalowska, Izabela, Webb, Andrew E., MacAogain, Micheál, Rogers, Thomas R., Windle, Henry, Kelleher, Dermot, O’Connell, Mary J., Loscher, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364705/
https://ncbi.nlm.nih.gov/pubmed/28335725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-017-0937-8
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