Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14

Bacterial-derived lipopolysaccharides (LPS) play an essential role in the inflammatory process of inflammatory bowel disease. A defective intestinal tight junction (TJ) barrier is an important pathogenic factor of inflammatory bowel disease and other inflammatory conditions of the gut. Despite its i...

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Detalhes bibliográficos
Main Authors: Guo, Shuhong, Al-Sadi, Rana, Said, Hamid M., Ma, Thomas Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562736/
https://ncbi.nlm.nih.gov/pubmed/23201091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.10.014
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