IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability Is Mediated by MEKK-1 Activation of Canonical NF-κB Pathway

IL-1β is a proinflammatory cytokine that plays a central role in the inflammatory process of the gut. IL-1β causes an increase in intestinal epithelial tight junction (TJ) permeability, but the intracellular pathways that mediate intestinal TJ permeability remain unclear. The major aims of this stud...

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Bibliographische Detailangaben
Hauptverfasser: Al-Sadi, Rana, Ye, Dongmei, Said, Hamid M., Ma, Thomas Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966790/
https://ncbi.nlm.nih.gov/pubmed/21048223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100371
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