Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification

Medial vascular calcification (MVC) is common in patients with chronic kidney disease, obesity, and aging. MVC is an actively regulated process that resembles skeletal mineralization, resulting from chondro-osteogenic transformation of vascular smooth muscle cells (VSMCs). Here, we used mineralizing...

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Hoofdauteurs: Kiffer-Moreira, Tina, Yadav, Manisha C, Zhu, Dongxing, Narisawa, Sonoko, Sheen, Campbell, Stec, Boguslaw, Cosford, Nicholas D., Dahl, Russell, Farquharson, Colin, Hoylaerts, Marc. F., MacRae, Vicky E., Millán, José Luis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562655/
https://ncbi.nlm.nih.gov/pubmed/22887744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1733
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