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Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development

Sphingosine-1-phosphate lyase (SPL) catalyzes the degradation of sphingosine-1-phosphate (S1P), a bioactive lipid that controls cell proliferation, migration and survival. Mice lacking SPL expression exhibit developmental abnormalities, runting and death during the perinatal period, suggesting that...

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Detalhes bibliográficos
Main Authors: Newbigging, Susan, Zhang, Meng, Saba, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562366/
https://ncbi.nlm.nih.gov/pubmed/23041657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2012.09.001
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