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Sphingosine-1-phosphate lyase in development and disease: Sphingolipid metabolism takes flight

Sphingosine-1-phosphate lyase (SPL) is a highly conserved enzyme that catalyses the final step of sphingolipid degradation, namely the irreversible cleavage of the carbon chain at position 2-3 of a long chain base phosphate (LCBP), thereby yielding a long-chain aldehyde and phosphoethanolamine. LCBP...

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Detalles Bibliográficos
Main Authors: Fyrst, Henrik, Saba, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749932/
https://ncbi.nlm.nih.gov/pubmed/18558101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.05.005
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