Rescue of nonsense mutations by amlexanox in human cells

BACKGROUND: Nonsense mutations are at the origin of many cancers and inherited genetic diseases. The consequence of nonsense mutations is often the absence of mutant gene expression due to the activation of an mRNA surveillance mechanism called nonsense-mediated mRNA decay (NMD). Strategies to rescu...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gonzalez-Hilarion, Sara, Beghyn, Terence, Jia, Jieshuang, Debreuck, Nadège, Berte, Gonzague, Mamchaoui, Kamel, Mouly, Vincent, Gruenert, Dieter C, Déprez, Benoit, Lejeune, Fabrice
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562214/
https://ncbi.nlm.nih.gov/pubmed/22938201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-7-58
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky