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Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth
The incidence of malignant melanoma has dramatically increased in recent years thus requiring the need for improved therapeutic strategies. In our efforts to design selective histone deactylase inhibitors (HDACI), we discovered that the aryl urea 1 is a modestly potent yet non-selective inhibitor. S...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562128/ https://ncbi.nlm.nih.gov/pubmed/23009203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301098e |
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