CHFR is important for the first wave of ubiquitination at DNA damage sites

Protein ubiquitination plays an important role in activating the DNA damage response and maintaining genomic stability. In response to DNA double-strand breaks (DSBs), a ubiquitination cascade occurs at DNA lesions. Here, we show that checkpoint with Forkhead-associated (FHA) and RING finger domain...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Chao, Wu, Jiaxue, Paudyal, Sharad C., You, Zhongsheng, Yu, Xiaochun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561977/
https://ncbi.nlm.nih.gov/pubmed/23268447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1278
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