NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, such as Crohn’s disease and colorectal cancer. Here, we show that dysbiosis caused by Nod2 deficiency gives rise to a reversible, communicable risk of colitis and colitis-ass...

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Hlavní autoři: Couturier-Maillard, Aurélie, Secher, Thomas, Rehman, Ateequr, Normand, Sylvain, De Arcangelis, Adèle, Haesler, Robert, Huot, Ludovic, Grandjean, Teddy, Bressenot, Aude, Delanoye-Crespin, Anne, Gaillot, Olivier, Schreiber, Stefan, Lemoine, Yves, Ryffel, Bernhard, Hot, David, Nùñez, Gabriel, Chen, Grace, Rosenstiel, Philip, Chamaillard, Mathias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561825/
https://ncbi.nlm.nih.gov/pubmed/23281400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62236
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