NOD2 Genetic Variants Predispose One of Two Familial Adenomatous Polyposis Siblings to Pouchitis Through Microbiome Dysbiosis

BACKGROUND AND AIMS: Individuals with familial adenomatous polyposis (FAP) may undergo a total proctocolectomy with ileal pouch-anal anastomosis (IPAA) to surgically treat their disease. Inflammation of the ileal pouch, termed pouchitis, is uncommon in FAP patients but prevalent in patients who rece...

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Bibliografske podrobnosti
izdano v:J Crohns Colitis
Main Authors: Schieffer, Kathleen M, Wright, Justin R, Harris, Leonard R, Deiling, Sue, Yang, Zhaohai, Lamendella, Regina, Yochum, Gregory S, Koltun, Walter A
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881696/
https://ncbi.nlm.nih.gov/pubmed/28633443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjx083
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