NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, such as Crohn’s disease and colorectal cancer. Here, we show that dysbiosis caused by Nod2 deficiency gives rise to a reversible, communicable risk of colitis and colitis-ass...

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Detalhes bibliográficos
Main Authors: Couturier-Maillard, Aurélie, Secher, Thomas, Rehman, Ateequr, Normand, Sylvain, De Arcangelis, Adèle, Haesler, Robert, Huot, Ludovic, Grandjean, Teddy, Bressenot, Aude, Delanoye-Crespin, Anne, Gaillot, Olivier, Schreiber, Stefan, Lemoine, Yves, Ryffel, Bernhard, Hot, David, Nùñez, Gabriel, Chen, Grace, Rosenstiel, Philip, Chamaillard, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561825/
https://ncbi.nlm.nih.gov/pubmed/23281400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62236
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