NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, such as Crohn’s disease and colorectal cancer. Here, we show that dysbiosis caused by Nod2 deficiency gives rise to a reversible, communicable risk of colitis and colitis-ass...

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Bibliografiske detaljer
Main Authors: Couturier-Maillard, Aurélie, Secher, Thomas, Rehman, Ateequr, Normand, Sylvain, De Arcangelis, Adèle, Haesler, Robert, Huot, Ludovic, Grandjean, Teddy, Bressenot, Aude, Delanoye-Crespin, Anne, Gaillot, Olivier, Schreiber, Stefan, Lemoine, Yves, Ryffel, Bernhard, Hot, David, Nùñez, Gabriel, Chen, Grace, Rosenstiel, Philip, Chamaillard, Mathias
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561825/
https://ncbi.nlm.nih.gov/pubmed/23281400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62236
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