Superior T memory stem cell persistence supports long-lived T cell memory

Long-lived memory T cells are able to persist in the host in the absence of antigen; however, the mechanism by which they are maintained is not well understood. Recently, a subset of human T cells, stem cell memory T cells (T(SCM) cells), was shown to be self-renewing and multipotent, thereby provid...

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Autori principali: Lugli, Enrico, Dominguez, Maria H., Gattinoni, Luca, Chattopadhyay, Pratip K., Bolton, Diane L., Song, Kaimei, Klatt, Nichole R., Brenchley, Jason M., Vaccari, Monica, Gostick, Emma, Price, David A., Waldmann, Thomas A., Restifo, Nicholas P., Franchini, Genoveffa, Roederer, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561805/
https://ncbi.nlm.nih.gov/pubmed/23281401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66327
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