Reduced Protection from Simian Immunodeficiency Virus SIV(mac251) Infection Afforded by Memory CD8(+) T Cells Induced by Vaccination during CD4(+) T-Cell Deficiency

Adaptive CD4(+) and CD8(+) T-cell responses have been associated with control of human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) replication. Here, we have designed a study with Indian rhesus macaques to more directly assess the role of CD8 SIV-specific responses in control of v...

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Hlavní autoři: Vaccari, Monica, Mattapallil, Joseph, Song, Kaimei, Tsai, Wen-Po, Hryniewicz, Anna, Venzon, David, Zanetti, Maurizio, Reimann, Keith A., Roederer, Mario, Franchini, Genoveffa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546957/
https://ncbi.nlm.nih.gov/pubmed/18667509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00893-08
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