Estimating the Infectivity of CCR5-Tropic Simian Immunodeficiency Virus SIV(mac251) in the Gut

CD4(+) T-cell depletion during acute human immunodeficiency virus infection occurs predominantly in the gastrointestinal mucosa. Using experimental data on SIV(mac251) viral load in blood and CD4(+) T cells in the jejunum, we modeled the kinetics of CD4(+) T-cell infection and death and estimated th...

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Détails bibliographiques
Auteurs principaux: Wilson, David P., Mattapallil, Joseph J., Lay, Matthew D. H., Zhang, Lei, Roederer, Mario, Davenport, Miles P.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951284/
https://ncbi.nlm.nih.gov/pubmed/17507462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01771-06
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