Superior T memory stem cell persistence supports long-lived T cell memory

Long-lived memory T cells are able to persist in the host in the absence of antigen; however, the mechanism by which they are maintained is not well understood. Recently, a subset of human T cells, stem cell memory T cells (T(SCM) cells), was shown to be self-renewing and multipotent, thereby provid...

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Detalhes bibliográficos
Main Authors: Lugli, Enrico, Dominguez, Maria H., Gattinoni, Luca, Chattopadhyay, Pratip K., Bolton, Diane L., Song, Kaimei, Klatt, Nichole R., Brenchley, Jason M., Vaccari, Monica, Gostick, Emma, Price, David A., Waldmann, Thomas A., Restifo, Nicholas P., Franchini, Genoveffa, Roederer, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561805/
https://ncbi.nlm.nih.gov/pubmed/23281401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66327
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