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A human memory T-cell subset with stem cell-like properties

Immunological memory is thought to depend upon a stem cell-like, self-renewing population of lymphocytes capable of differentiating into effector cells in response to antigen re-exposure. Here we describe a long-lived human memory T-cell population that displays enhanced self-renewal and multipotent...

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Detalhes bibliográficos
Main Authors: Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M., Quigley, Máire F., Almeida, Jorge R., Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C., Price, David A., June, Carl H., Marincola, Francesco M., Roederer, Mario, Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192229/
https://ncbi.nlm.nih.gov/pubmed/21926977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2446
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