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Hyperactivation of the Mammalian Degenerin MDEG Promotes Caspase-8 Activation and Apoptosis
Intracellular calcium overload plays a critical role in numerous pathological syndromes such as heart failure, brain ischemia, and stroke. Hyperactivation of the acid-sensing ion channels including degenerin/epithelial amiloride-sensitive sodium (DEG/ENaC) channels has been shown to elevate intracel...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561519/ https://ncbi.nlm.nih.gov/pubmed/23239879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441063 |
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