Structures of Endonuclease V with DNA Reveal Initiation of Deaminated Adenine Repair

Endonuclease V (EndoV) initiates a major base repair pathway for nitrosative deamination resulting from endogenous processes and increased by oxidative stress from mitochondrial dysfunction or inflammatory responses. We solved the crystal structures of Thermotoga maritima EndoV in complex with a hyp...

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Autori principali: Dalhus, Bjorn, Arvai, Andrew S., Rosnes, Ida, Olsen, Oyvind E., Backe, Paul H., Alseth, Ingrun, Gao, Honghai, Cao, Weiguo, Tainer, John A., Bjoras, Magnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560532/
https://ncbi.nlm.nih.gov/pubmed/19136958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1538
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