Organ Injury and Cytokine Release Caused by Peptidoglycan Are Dependent on the Structural Integrity of the Glycan Chain

Several studies have implicated a role of peptidoglycan (PepG) as a pathogenicity factor in sepsis and organ injury, in part by initiating the release of inflammatory mediators. We wanted to elucidate the structural requirements of PepG to trigger inflammatory responses and organ injury. Injection o...

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Bibliographic Details
Main Authors: Myhre, Anders E., Stuestøl, Jon Fredrik, Dahle, Maria K., Øverland, Gunhild, Thiemermann, Christoph, Foster, Simon J., Lilleaasen, Per, Aasen, Ansgar O., Wang, Jacob E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC356048/
https://ncbi.nlm.nih.gov/pubmed/14977933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1311-1317.2004
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