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Effects of Forskolin on Kupffer Cell Production of Interleukin-10 and Tumor Necrosis Factor Alpha Differ from Those of Endogenous Adenylyl Cyclase Activators: Possible Role for Adenylyl Cyclase 9

Proinflammatory cytokines like tumor necrosis factor alpha (TNF-α) that are released from Kupffer cells may trigger liver inflammation and damage. Hence, endogenous mechanisms for limiting TNF-α expression are crucial for avoiding the development of sepsis. Such mechanisms include the anti-inflammat...

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Detalhes bibliográficos
Main Authors: Dahle, Maria K., Myhre, Anders E., Aasen, Ansgar O., Wang, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273915/
https://ncbi.nlm.nih.gov/pubmed/16239525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.11.7290-7296.2005
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