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Organ Injury and Cytokine Release Caused by Peptidoglycan Are Dependent on the Structural Integrity of the Glycan Chain

Several studies have implicated a role of peptidoglycan (PepG) as a pathogenicity factor in sepsis and organ injury, in part by initiating the release of inflammatory mediators. We wanted to elucidate the structural requirements of PepG to trigger inflammatory responses and organ injury. Injection o...

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Detalhes bibliográficos
Main Authors: Myhre, Anders E., Stuestøl, Jon Fredrik, Dahle, Maria K., Øverland, Gunhild, Thiemermann, Christoph, Foster, Simon J., Lilleaasen, Per, Aasen, Ansgar O., Wang, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356048/
https://ncbi.nlm.nih.gov/pubmed/14977933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1311-1317.2004
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