The Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway Is Activated by Lipoteichoic Acid and Plays a Role in Kupffer Cell Production of Interleukin-6 (IL-6) and IL-10

Sepsis caused by gram-positive bacteria lacking lipopolysaccharide (LPS) has become a major and increasing cause of mortality in intensive-care units. We have recently demonstrated that the gram-positive-specific bacterial cell wall component lipoteichoic acid (LTA) stimulates the release of the pro...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Dahle, Maria K., Øverland, Gunhild, Myhre, Anders E., Stuestøl, Jon Fredrik, Hartung, Thomas, Krohn, Claus Danckert, Mathiesen, Øystein, Wang, Jacob E., Aasen, Ansgar O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15385469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.10.5704-5711.2004
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