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Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides
The effects of reducing the molecular weight of the antileishmanial compound DB766 on DNA binding affinity, antileishmanial activity and cytotoxicity are reported. The bis-arylimidamides were prepared by the coupling of aryl S-(2-naphthylmethyl)thioimidates with the corresponding amines. Specificall...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560421/ https://ncbi.nlm.nih.gov/pubmed/22840696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.06.058 |
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