Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein

BACKGROUND: The development of vectors for cell-specific gene delivery is a major goal of gene therapeutic strategies. Transferrin receptor (TfR) is an endocytic receptor and identified as tumor relative specific due to its overexpression on most tumor cells or tissues, and TfR binds and intakes of...

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Bibliographic Details
Main Authors: Ye, Qing, Hu, Heyu, Wang, Zhihua, Lu, Tong, Hu, Zhiquan, Zeng, Xing, Zhang, Shu, Liu, Jing, Lei, Ping, Wang, Cong-Yi, Ye, Zhangqun, Shen, Guanxin
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560209/
https://ncbi.nlm.nih.gov/pubmed/23192001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-91
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