Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein

BACKGROUND: The development of vectors for cell-specific gene delivery is a major goal of gene therapeutic strategies. Transferrin receptor (TfR) is an endocytic receptor and identified as tumor relative specific due to its overexpression on most tumor cells or tissues, and TfR binds and intakes of...

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Detalhes bibliográficos
Main Authors: Ye, Qing, Hu, Heyu, Wang, Zhihua, Lu, Tong, Hu, Zhiquan, Zeng, Xing, Zhang, Shu, Liu, Jing, Lei, Ping, Wang, Cong-Yi, Ye, Zhangqun, Shen, Guanxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560209/
https://ncbi.nlm.nih.gov/pubmed/23192001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-91
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