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Distinct Sites within the VCAM-1 Cytoplasmic Domain Regulate VCAM-1 Activation of Calcium Fluxes versus Rac1 during Leukocyte Transendothelial Migration
Vascular adhesion molecules regulate the migration of leukocytes from the blood into tissue during inflammation. Leukocyte binding to vascular cell adhesion molecule-1 (VCAM-1) activates signals in endothelial cells, including Rac1 and calcium fluxes. These VCAM-1 signals are required for leukocyte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558628/ https://ncbi.nlm.nih.gov/pubmed/22970700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300925r |
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