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Endothelial cell PTP1B regulates leukocyte recruitment during allergic inflammation

Pulmonary eosinophilia is a consistent hallmark of allergic lung inflammation. Infiltration of eosinophils into ovalbumin (OVA)-challenged lungs is dependent on the adhesion molecule vascular cell adhesion molecule-1 (VCAM-1) on endothelial cells. Ligation of VCAM-1 activates endothelial cell protei...

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Autores principales: Berdnikovs, Sergejs, Abdala-Valencia, Hiam, Cook-Mills, Joan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567363/
https://ncbi.nlm.nih.gov/pubmed/23275627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00375.2012
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